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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D2
All Species:
9.09
Human Site:
Y79
Identified Species:
33.33
UniProt:
Q9BYX2
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYX2
NP_060891.3
917
104105
Y79
D
E
R
K
C
Q
L
Y
Y
S
R
T
A
Q
D
Chimpanzee
Pan troglodytes
XP_001158298
917
104061
Y79
D
E
R
K
C
Q
L
Y
Y
S
R
T
A
Q
D
Rhesus Macaque
Macaca mulatta
XP_001113380
915
104200
Y77
D
E
R
K
C
Q
L
Y
Y
S
R
T
A
Q
D
Dog
Lupus familis
XP_538748
927
104830
R77
K
C
H
L
Y
Y
S
R
T
A
Q
D
A
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U0J8
965
109931
L79
S
P
Q
D
A
L
P
L
G
H
L
D
I
A
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516235
726
83877
P37
Q
A
A
N
Q
P
A
P
V
H
A
S
I
H
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795416
1076
123131
I164
A
A
K
Q
A
E
Q
I
K
Q
K
S
F
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.7
82.9
N.A.
38.9
N.A.
N.A.
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
99.7
97.1
88.3
N.A.
57.4
N.A.
N.A.
51.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
100
100
6.6
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
29
15
0
29
0
15
0
0
15
15
0
58
15
0
% A
% Cys:
0
15
0
0
43
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
0
0
15
0
0
0
0
0
0
0
29
0
0
58
% D
% Glu:
0
43
0
0
0
15
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
29
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
0
0
29
0
0
% I
% Lys:
15
0
15
43
0
0
0
0
15
0
15
0
0
0
15
% K
% Leu:
0
0
0
15
0
15
43
15
0
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
0
0
0
0
0
15
15
% N
% Pro:
0
15
0
0
0
15
15
15
0
0
0
0
0
0
15
% P
% Gln:
15
0
15
15
15
43
15
0
0
15
15
0
0
43
0
% Q
% Arg:
0
0
43
0
0
0
0
15
0
0
43
0
0
0
0
% R
% Ser:
15
0
0
0
0
0
15
0
0
43
0
29
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
15
0
0
43
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
15
0
43
43
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _